If you have noticed that your iPad (or iPhone) home button isn't as responsive as it once was, you may need to recalibrate it. You've probably pressed your iPad 2 home button 50 times each day since you bought it, so after 10,000 or so presses it may need a recalibration. I use gestures on my jailbroken iPad 2 (iOS 4.3.3) and prpbably press my home button much less on my iPad as compared to my iPhone 4S. Check out this video from Jeff at Jailbreak Movies on YouTube.
Here are the steps to recalibrate your iPad 2 home button:
1. Open any application (stocks app recommended)
2. Press/hold the power button until the "slide to shutdown" bar appears.
3. Release Power button
4. Press and hold Home button lightly until screen returns to icon screen
5. Enjoy your functioning home button!